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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
23.94
Human Site:
Y692
Identified Species:
40.51
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
Y692
G
R
A
T
I
G
R
Y
F
N
E
G
T
V
L
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
Y692
G
R
A
T
I
G
R
Y
F
N
E
G
T
V
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
Y789
G
R
A
T
I
G
R
Y
F
N
E
G
T
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
Y686
G
K
A
A
I
G
R
Y
F
T
E
G
T
V
L
Rat
Rattus norvegicus
NP_001099948
974
110023
Y657
G
K
A
T
I
A
R
Y
F
T
E
G
T
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
E633
V
L
S
S
G
S
D
E
E
C
A
I
C
L
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
Y682
G
K
A
V
I
S
R
Y
V
D
E
G
T
V
L
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
L661
Q
C
C
C
H
P
S
L
V
G
N
Y
T
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
F734
S
R
T
L
F
A
Q
F
L
H
Q
R
A
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
Y770
G
R
L
A
V
S
K
Y
F
Q
Q
G
S
V
L
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
Q548
M
K
M
V
T
V
L
Q
D
G
E
D
F
D
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
G630
L
V
A
A
L
Q
D
G
E
D
F
D
C
P
I
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
L539
I
G
V
V
I
C
Q
L
C
N
D
E
A
E
E
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
N866
A
K
R
T
L
F
D
N
M
Q
A
G
T
V
M
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
80
80
N.A.
0
N.A.
66.6
6.6
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
20
N.A.
80
6.6
N.A.
33.3
N.A.
N.A.
73.3
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
6.6
N.A.
N.A.
6.6
13.3
26.6
P-Site Similarity:
13.3
N.A.
N.A.
26.6
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
50
22
0
15
0
0
0
0
15
0
15
8
8
% A
% Cys:
0
8
8
8
0
8
0
0
8
8
0
0
15
0
8
% C
% Asp:
0
0
0
0
0
0
22
0
8
15
8
15
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
8
15
0
50
8
0
15
8
% E
% Phe:
0
0
0
0
8
8
0
8
43
0
8
0
8
0
0
% F
% Gly:
50
8
0
0
8
29
0
8
0
15
0
58
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
50
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
36
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
8
15
0
8
15
8
0
0
0
0
8
50
% L
% Met:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
29
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
0
0
0
8
15
8
0
15
15
0
0
0
0
% Q
% Arg:
0
36
8
0
0
0
43
0
0
0
0
8
0
0
8
% R
% Ser:
8
0
8
8
0
22
8
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
36
8
0
0
0
0
15
0
0
58
0
0
% T
% Val:
8
8
8
22
8
8
0
0
15
0
0
0
0
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _